Women are two to three times more likely to experience depression at some point in their lives than men. There are some reasons that play into depression being more common for women.
When estrogen levels naturally ebb during a woman’s reproductive cycle, stress increases, and she might feel less emotionally resilient and be at greater risk of becoming depressed.
When estrogen permanently drops in perimenopause and menopause, women are up to five times more likely to develop major depressive disorder (MDD) than at other times in their lives.